Oxidized low density lipoprotein induces differentiation and adhesion of human monocytes and the monocytic cell line U937.

Hypercholesterolemia is a major risk factor for development of atherosclerosis. In experimental animals fed a high-cholesterol diet, monocytes adhere to the arterial endothelium and penetrate into the intima where they differentiate into macrophages and ingest lipids thus giving rise to fatty streak...

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Bibliographic Details
Main Authors: Frostegård, J, Nilsson, J, Haegerstrand, A, Hamsten, A, Wigzell, H, Gidlund, M
Format: Artigo
Language:Inglês
Published: 1990
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC53377/
https://ncbi.nlm.nih.gov/pubmed/2300583
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