CD161(+) Tconv and CD161(+) Treg Share a Transcriptional and Functional Phenotype despite Limited Overlap in TCRβ Repertoire

Human regulatory T cells (Treg) are important in immune regulation, but can also show plasticity in specific settings. CD161 is a lectin-like receptor and its expression identifies an effector-like Treg population. Here, we determined how CD161(+) Treg relate to CD161(+) conventional T cells (Tconv)...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Duurland, Chantal L., Brown, Chrysothemis C., O’Shaughnessy, Ryan F. L., Wedderburn, Lucy R.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5337494/
https://ncbi.nlm.nih.gov/pubmed/28321213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00103
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