Adjusted Particle Size Eliminates the Need of Linkage of Antigen and Adjuvants for Appropriated T Cell Responses in Virus-Like Particle-Based Vaccines

Since the discovery of the first virus-like particle (VLP) derived from hepatitis B virus in 1980 (1), the field has expanded substantially. Besides successful use of VLPs as safe autologous virus-targeting vaccines, the powerful immunogenicity of VLPs has been also harnessed to generate immune resp...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Gomes, Ariane C., Flace, Anna, Saudan, Philippe, Zabel, Franziska, Cabral-Miranda, Gustavo, Turabi, Aadil El, Manolova, Vania, Bachmann, Martin F.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5337491/
https://ncbi.nlm.nih.gov/pubmed/28321220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00226
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