ALK oncoproteins in atypical inflammatory myofibroblastic tumours: novel RRBP1-ALK fusions in epithelioid inflammatory myofibroblastic sarcoma

ALK oncogenic activation mechanisms were characterized in four conventional spindle-cell inflammatory myofibroblastic tumours (IMT) and five atypical IMT, each of which had ALK genomic perturbations. Constitutively activated ALK oncoproteins were purified by ALK immunoprecipitation and electrophores...

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Bibliographic Details
Published in:J Pathol
Main Authors: Lee, Jen-Chieh, Li, Chien-Feng, Huang, Hsuan-Ying, Zhu, Mei-Jun, Mariño-Enríquez, Adrián, Lee, Chung-Ta, Ou, Wen-Bin, Hornick, Jason L., Fletcher, Jonathan A.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5337428/
https://ncbi.nlm.nih.gov/pubmed/27874193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4836
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