Bone Mass and Strength are Significantly Improved in Mice Overexpressing Human WNT16 in Osteocytes

Recently, we demonstrated that osteoblast-specific overexpression of human WNT16 increased both cortical and trabecular bone mass and structure in mice. To further identify the cell-specific role of Wnt16 in bone homeostasis, we created transgenic (TG) mice over-expressing human WNT16 in osteocytes...

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Detalhes bibliográficos
Publicado no:Calcif Tissue Int
Main Authors: Alam, Imranul, Reilly, Austin M., Alkhouli, Mohammed, Gerard-O’Riley, Rita L., Kasipathi, Charishma, Oakes, Dana K., Wright, Weston B., Acton, Dena, McQueen, Amie K., Patel, Bhavmik, Lim, Kyung-Eun, Robling, Alexander G., Econs, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5337173/
https://ncbi.nlm.nih.gov/pubmed/28013361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00223-016-0225-4
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