Neutralizing Anti-Interleukin-1β Antibodies Reduce Ischemia-Related Interleukin-1β Transport across the Blood-Brain Barrier in Fetal Sheep

Hypoxic ischemic insults predispose to perinatal brain injury. Pro-inflammatory cytokines are important in the evolution of this injury. Interleukin-1β (IL-1β) is a key mediator of inflammatory responses and elevated IL-1β levels in brain correlate with adverse neurodevelopmental outcomes after brai...

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Vydáno v:Neuroscience
Hlavní autoři: Patra, Aparna, Chen, Xiaodi, Sadowska, Grazyna B., Zhang, Jiyong, Lim, Yow-Pin, Padbury, James F., Banks, William A., Stonestreet, Barbara S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5337150/
https://ncbi.nlm.nih.gov/pubmed/28089577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2016.12.051
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