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Expression cloning of a cDNA encoding the murine interleukin 4 receptor based on ligand binding.

Interleukin 4 (IL-4) is a potent mediator of growth and differentiation for various lymphoid and myeloid cells. To isolate a cDNA encoding the murine IL-4 receptor, we have developed an expression cloning method that uses biotinylated ligand as a probe and that may be generally applicable to cloning...

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Published in:Proc Natl Acad Sci U S A
Main Authors: Harada, N, Castle, B E, Gorman, D M, Itoh, N, Schreurs, J, Barrett, R L, Howard, M, Miyajima, A
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1990
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53367/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2405398/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.3.857
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