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Opposing regulation of dopaminergic activity and exploratory motor behavior by forebrain and brainstem cholinergic circuits

Dopamine transmission is critical for exploratory motor behavior. A key regulator is acetylcholine: forebrain acetylcholine regulates striatal dopamine release, whereas brainstem cholinergic inputs regulate the transition from tonic to burst firing modes of dopamine neurons. How these sources of cho...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Patel, Jyoti C., Rossignol, Elsa, Rice, Margaret E., Machold, Robert P.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5336695/
https://ncbi.nlm.nih.gov/pubmed/23132022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2144
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