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Threshold levels of extracellular l-arginine that trigger NOS-mediated ROS/RNS production in cardiac ventricular myocytes

l-Arginine (L-Arg) is the substrate for nitric oxide synthase (NOS) to produce nitric oxide (NO), a signaling molecule that is key in cardiovascular physiology and pathology. In cardiac myocytes, L-Arg is incorporated from the circulation through the functioning of system-y(+) cationic amino acid tr...

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Опубликовано в: :Am J Physiol Cell Physiol
Главные авторы: Ramachandran, Jayalakshmi, Peluffo, R. Daniel
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5336593/
https://ncbi.nlm.nih.gov/pubmed/27903582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00150.2016
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