Long-term high-fat diet induces hippocampal microvascular insulin resistance and cognitive dysfunction

Insulin action on hippocampus improves cognitive function, and obesity and type 2 diabetes are associated with decreased cognitive function. Cerebral microvasculature plays a critical role in maintaining cerebral vitality and function by supplying nutrients, oxygen, and hormones such as insulin to c...

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Bibliographic Details
Published in:Am J Physiol Endocrinol Metab
Main Authors: Fu, Zhuo, Wu, Jing, Nesil, Tanseli, Li, Ming D., Aylor, Kevin W., Liu, Zhenqi
Format: Artigo
Language:Inglês
Published: American Physiological Society 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5336564/
https://ncbi.nlm.nih.gov/pubmed/27899343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00297.2016
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