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Bioequivalence Methodologies for Topical Drug Products: In Vitro and Ex Vivo Studies with a Corticosteroid and an Anti-Fungal Drug

OBJECTIVE: To examine whether in vitro and ex vivo measurements of topical drug product performance correlate with in vivo outcomes, such that more efficient experimental approaches can be reliably and reproducibly used to establish (in)equivalence between formulations for skin application. MATERIAL...

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Bibliographic Details
Published in:Pharm Res
Main Authors: Leal, Leila Bastos, Cordery, Sarah F., Delgado-Charro, M. Begoña, Bunge, Annette L., Guy, Richard H.
Format: Artigo
Language:Inglês
Published: Springer US 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5336544/
https://ncbi.nlm.nih.gov/pubmed/28097506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-017-2099-1
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