DNA methylation-derived neutrophil-to-lymphocyte ratio: an epigenetic tool to explore cancer inflammation and outcomes

BACKGROUND: The peripheral blood neutrophil–to-lymphocyte ratio (NLR) is a cytological marker of both inflammation and poor outcomes in cancer patients. DNA methylation is a key element of the epigenetic program defining different leukocyte subtypes and may provide an alternative to cytology in asse...

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Udgivet i:Cancer Epidemiol Biomarkers Prev
Main Authors: Koestler, Devin C., Usset, Joseph, Christensen, Brock C., Marsit, Carmen J., Karagas, Margaret R., Kelsey, Karl T., Wiencke, John K.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5336518/
https://ncbi.nlm.nih.gov/pubmed/27965295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-16-0461
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