Higher serum DHEA concentrations before and after SSRI treatment are associated with remission of major depression

BACKGROUND: Dehydroepiandrosterone (DHEA) and its sulfated ester DHEA-sulfate (DHEA-S), (together DHEA[S]), are the most abundant adrenal steroids in humans and are found in blood and the brain, where they function as neurosteroids with direct receptor affinities. Preclinical studies suggest that DH...

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Pubblicato in:Psychoneuroendocrinology
Autori principali: Hough, Christina M., Lindqvist, Daniel, Epel, Elissa S., St. Denis, Molly, Reus, Victor I., Bersani, F. Saverio, Rosser, Rebecca, Mahan, Laura, Burke, Heather M., Wolkowitz, Owen M., Mellon, Synthia H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5336487/
https://ncbi.nlm.nih.gov/pubmed/28038403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psyneuen.2016.11.035
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