Uncovering precision phenotype-biomarker associations in traumatic brain injury using topological data analysis

BACKGROUND: Traumatic brain injury (TBI) is a complex disorder that is traditionally stratified based on clinical signs and symptoms. Recent imaging and molecular biomarker innovations provide unprecedented opportunities for improved TBI precision medicine, incorporating patho-anatomical and molecul...

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Published in:PLoS One
Main Authors: Nielson, Jessica L., Cooper, Shelly R., Yue, John K., Sorani, Marco D., Inoue, Tomoo, Yuh, Esther L., Mukherjee, Pratik, Petrossian, Tanya C., Paquette, Jesse, Lum, Pek Y., Carlsson, Gunnar E., Vassar, Mary J., Lingsma, Hester F., Gordon, Wayne A., Valadka, Alex B., Okonkwo, David O., Manley, Geoffrey T., Ferguson, Adam R.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5336356/
https://ncbi.nlm.nih.gov/pubmed/28257413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169490
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