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Transcriptional signatures of unfolded protein response implicate the limitation of animal models in pathophysiological studies

BACKGROUND: The unfolded protein response (UPR) refers to intracellular stress signaling pathways that protect cells from the stress caused by accumulation of unfolded or misfolded proteins in the endoplasmic reticulum (ER). The UPR signaling is crucially involved in the initiation and progression o...

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Detalhes bibliográficos
Publicado no:Environ Dis
Main Authors: Zheng, Ze, Wang, Guohui, Li, Li, Tseng, Jeffery, Sun, Fei, Chen, Xuequn, Chang, Lin, Heng, Henry, Zhang, Kezhong
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5336312/
https://ncbi.nlm.nih.gov/pubmed/28265594
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