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Idelalisib and caffeine reduce suppression of T cell responses mediated by activated chronic lymphocytic leukemia cells

Chronic lymphocytic leukemia (CLL) is associated with T cell dysfunction. Activated CLL cells are found within the lymphoid tumor micro-environment and overcoming immuno-suppression induced by these cells may improve anti-CLL immune responses. However, the mechanisms by which activated CLL cells inh...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hock, Barry D., MacPherson, Sean A., McKenzie, Judith L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5336221/
https://ncbi.nlm.nih.gov/pubmed/28257435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172858
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