The Expanding Family of Natural Anion Channelrhodopsins Reveals Large Variations in Kinetics, Conductance, and Spectral Sensitivity

Natural anion channelrhodopsins (ACRs) discovered in the cryptophyte alga Guillardia theta generate large hyperpolarizing currents at membrane potentials above the Nernst equilibrium potential for Cl(−) and thus can be used as efficient inhibitory tools for optogenetics. We have identified and chara...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Govorunova, Elena G., Sineshchekov, Oleg A., Rodarte, Elsa M., Janz, Roger, Morelle, Olivier, Melkonian, Michael, Wong, Gane K.-S., Spudich, John L.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5335703/
https://ncbi.nlm.nih.gov/pubmed/28256618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43358
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