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SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules

To be effective as a drug, a potent molecule must reach its target in the body in sufficient concentration, and stay there in a bioactive form long enough for the expected biologic events to occur. Drug development involves assessment of absorption, distribution, metabolism and excretion (ADME) incr...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Daina, Antoine, Michielin, Olivier, Zoete, Vincent
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5335600/
https://ncbi.nlm.nih.gov/pubmed/28256516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42717
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