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PAR1 activation induces rapid changes in glutamate uptake and astrocyte morphology

The G-protein coupled, protease-activated receptor 1 (PAR1) is a membrane protein expressed in astrocytes. Fine astrocytic processes are in tight contact with neurons and blood vessels and shape excitatory synaptic transmission due to their abundant expression of glutamate transporters. PAR1 is prot...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Sweeney, Amanda M., Fleming, Kelsey E., McCauley, John P., Rodriguez, Marvin F., Martin, Elliot T., Sousa, Alioscka A., Leapman, Richard D., Scimemi, Annalisa
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5335386/
https://ncbi.nlm.nih.gov/pubmed/28256580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43606
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