A Core Regulatory Circuit in Glioblastoma Stem Cells Links MAPK Activation to a Transcriptional Program of Neural Stem Cell Identity

Glioblastoma, the most common primary malignant brain tumor, harbors a small population of tumor initiating cells (glioblastoma stem cells) that have many properties similar to neural stem cells. To investigate common regulatory networks in both neural and glioblastoma stem cells, we subjected both...

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Publicado no:Sci Rep
Main Authors: Riddick, Gregory, Kotliarova, Svetlana, Rodriguez, Virginia, Kim, H. S., Linkous, Amanda, Storaska, Andrew J., Ahn, Susie, Walling, Jennifer, Belova, Galina, Fine, Howard A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5335262/
https://ncbi.nlm.nih.gov/pubmed/28256619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43605
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