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Diadenosine tetraphosphate (Ap(4)A) inhibits ATP-induced excitotoxicity: a neuroprotective strategy for traumatic spinal cord injury treatment

Reducing cell death during the secondary injury is a major priority in the development of a cure for traumatic spinal cord injury (SCI). One of the earliest processes that follow SCI is the excitotoxicity resulting from the massive release of excitotoxicity mediators, including ATP, which induce an...

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Détails bibliographiques
Publié dans:Purinergic Signal
Auteurs principaux: Reigada, David, Navarro-Ruiz, Rosa María, Caballero-López, Marcos Javier, Del Águila, Ángela, Muñoz-Galdeano, Teresa, Maza, Rodrigo M., Nieto-Díaz, Manuel
Format: Artigo
Langue:Inglês
Publié: Springer Netherlands 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334201/
https://ncbi.nlm.nih.gov/pubmed/27761681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-016-9541-4
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