2′,3′-O-Substituted ATP derivatives as potent antagonists of purinergic P2X3 receptors and potential analgesic agents

Blocking membrane currents evoked by the activation of purinergic P2X3 receptors localized on nociceptive neurons represents a promising strategy for the development of agents useful for the treatment of chronic pain conditions. Among compounds endowed with such antagonistic action, 2′,3′-O-(2,4,6-t...

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Vydáno v:Purinergic Signal
Hlavní autoři: Dal Ben, Diego, Marchenkova, Anna, Thomas, Ajiroghene, Lambertucci, Catia, Spinaci, Andrea, Marucci, Gabriella, Nistri, Andrea, Volpini, Rosaria
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Netherlands 2016
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334199/
https://ncbi.nlm.nih.gov/pubmed/27757785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-016-9539-y
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