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Modeling and optimization of nanoemulsion containing Sorafenib for cancer treatment by response surface methodology

The aim of this study is the development of nanoemulsions for intravenous administration of Sorafenib, which is a poorly soluble drug with no parenteral treatment. The formulation was prepared by a high energy emulsification method and optimized by response surface methodology. The effects of overhe...

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Bibliographische Detailangaben
Veröffentlicht in:Chem Cent J
Hauptverfasser: Izadiyan, Zahra, Basri, Mahiran, Fard Masoumi, Hamid Reza, Abedi Karjiban, Roghayeh, Salim, Norazlinaliza, Shameli, Kamyar
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334191/
https://ncbi.nlm.nih.gov/pubmed/28293282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13065-017-0248-6
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