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Proof of the Quantitative Potential of Immunofluorescence by Mass Spectrometry

Protein expression in formalin-fixed, paraffin-embedded (FFPE) patient tissue is routinely measured by Immunohistochemistry (IHC). However, IHC has been shown to be subject to variability in sensitivity, specificity and reproducibility, and is generally, at best, considered semi-quantitative. Mass s...

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Bibliographic Details
Published in:Lab Invest
Main Authors: Toki, Maria I., Cecchi, Fabiola, Hembrough, Todd, Syrigos, Konstantinos N., Rimm, David L.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334147/
https://ncbi.nlm.nih.gov/pubmed/28092364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2016.148
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