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Next generation sequencing identifies ‘interactome’ signatures in relapsed and refractory metastatic colorectal cancer

BACKGROUND: In the management of metastatic colorectal cancer (mCRC), KRAS, NRAS and BRAF mutational status individualizes therapeutic options and identify a cohort of patients (pts) with an aggressive clinical course. We hypothesized that relapsed and refractory mCRC pts develop unique mutational s...

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Detalhes bibliográficos
Publicado no:J Gastrointest Oncol
Main Authors: Johnson, Benny, Cooke, Laurence, Mahadevan, Daruka
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334057/
https://ncbi.nlm.nih.gov/pubmed/28280605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jgo.2016.09.05
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