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G-quartet oligonucleotide mediated delivery of proteins into photoreceptors and retinal pigment epithelium via intravitreal injection

There is currently no available method to efficiently deliver proteins across the plasma membrane of photoreceptor or retinal pigment epithelium (RPE) cells in vivo. Thus, current clinical application of recombinant proteins in ophthalmology is limited to the use of proteins that perform their biolo...

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Bibliographische Detailangaben
Veröffentlicht in:Exp Eye Res
Hauptverfasser: Leaderer, Derek, Cashman, Siobhan M., Kumar-Singh, Rajendra
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334003/
https://ncbi.nlm.nih.gov/pubmed/26923800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2016.02.009
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