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G-quartet oligonucleotide mediated delivery of proteins into photoreceptors and retinal pigment epithelium via intravitreal injection

There is currently no available method to efficiently deliver proteins across the plasma membrane of photoreceptor or retinal pigment epithelium (RPE) cells in vivo. Thus, current clinical application of recombinant proteins in ophthalmology is limited to the use of proteins that perform their biolo...

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Detalhes bibliográficos
Publicado no:Exp Eye Res
Main Authors: Leaderer, Derek, Cashman, Siobhan M., Kumar-Singh, Rajendra
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334003/
https://ncbi.nlm.nih.gov/pubmed/26923800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2016.02.009
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