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G-quartet oligonucleotide mediated delivery of proteins into photoreceptors and retinal pigment epithelium via intravitreal injection

There is currently no available method to efficiently deliver proteins across the plasma membrane of photoreceptor or retinal pigment epithelium (RPE) cells in vivo. Thus, current clinical application of recombinant proteins in ophthalmology is limited to the use of proteins that perform their biolo...

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Detalles Bibliográficos
Publicado en:Exp Eye Res
Autores principales: Leaderer, Derek, Cashman, Siobhan M., Kumar-Singh, Rajendra
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334003/
https://ncbi.nlm.nih.gov/pubmed/26923800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2016.02.009
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