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Platelets from pulmonary hypertension patients show increased mitochondrial reserve capacity

Accumulating evidence suggests that altered cellular metabolism is systemic in pulmonary hypertension (PH) and central to disease pathogenesis. However, bioenergetic changes in PH patients and their association with disease severity remain unclear. Here, we hypothesize that alteration in bioenergeti...

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Detalhes bibliográficos
Publicado no:JCI Insight
Principais autores: Nguyen, Quyen L., Corey, Catherine, White, Pamela, Watson, Annie, Gladwin, Mark T., Simon, Marc A., Shiva, Sruti
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5333965/
https://ncbi.nlm.nih.gov/pubmed/28289721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.91415
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