CSB ablation induced apoptosis is mediated by increased endoplasmic reticulum stress response

The DNA repair protein Cockayne syndrome group B (CSB) has been recently identified as a promising anticancer target. Suppression, by antisense technology, of this protein causes devastating effects on tumor cells viability, through a massive induction of apoptosis, while being non-toxic to non-tran...

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Vydáno v:PLoS One
Hlavní autoři: Caputo, Manuela, Balzerano, Alessio, Arisi, Ivan, D’Onofrio, Mara, Brandi, Rossella, Bongiorni, Silvia, Brancorsini, Stefano, Frontini, Mattia, Proietti-De-Santis, Luca
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5333825/
https://ncbi.nlm.nih.gov/pubmed/28253359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172399
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