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Involvement of Tiam1, RhoG and ELMO2/ILK in Rac1-mediated Phagocytosis in Human Trabecular Meshwork Cells

We previously demonstrated that an αvβ5 integrin/FAK- mediated pathway regulated the phagocytic properties of human trabecular meshwork (HTM) cells. Here we demonstrate that this process is mediated by Rac-1 and a previously unreported signaling pathway that utilizes the Tiam1 as well as a novel ILK...

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Detalhes bibliográficos
Publicado no:Exp Cell Res
Main Authors: Peotter, Jennifer L., Phillips, Jenny, Tong, Tiegang, Dimeo, Kaylee, Gonzalez, Jose M., Peters, Donna M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5333770/
https://ncbi.nlm.nih.gov/pubmed/27539661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2016.08.009
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