β-Thalassemia Distribution in the Old World: an Ancient Disease Seen from a Historical Standpoint

BACKGROUND: Haemoglobinopathies constitute the commonest recessive monogenic disorders worldwide, and the treatment of affected individuals presents a substantial global disease burden. β-thalassaemia is characterised by the reduced synthesis (β(+)) or absence (β(o)) of the β-globin chains in the Hb...

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Publicado en:Mediterr J Hematol Infect Dis
Autores principales: De Sanctis, Vincenzo, Kattamis, Christos, Canatan, Duran, Soliman, Ashraf T., Elsedfy, Heba, Karimi, Mehran, Daar, Shahina, Wali, Yasser, Yassin, Mohamed, Soliman, Nada, Sobti, Praveen, Al Jaouni, Soad, El Kholy, Mohamed, Fiscina, Bernadette, Angastiniotis, Michael
Formato: Artigo
Lenguaje:Inglês
Publicado: Università Cattolica del Sacro Cuore 2017
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Review Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5333734/
https://ncbi.nlm.nih.gov/pubmed/28293406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4084/MJHID.2017.018
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