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Proteomics insights into DNA damage response and translating this knowledge to clinical strategies
Genomic instability is a critical driver in the process of cancer formation. At the same time, inducing DNA damage by irradiation or genotoxic compounds constitutes a key therapeutic strategy to kill fast‐dividing cancer cells. Sensing of DNA lesions initiates a complex set of signalling pathways, c...
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| Опубликовано в: : | Proteomics |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley and Sons Inc.
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5333460/ https://ncbi.nlm.nih.gov/pubmed/27682984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201600018 |
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