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Rhein Inhibits Autophagy in Rat Renal Tubular Cells by Regulation of AMPK/mTOR Signaling

Rhubarb and its bioactive component rhein are frequently used for the treatment of chronic kidney diseases (CKD) in eastern Asia countries. However, the potential therapeutic mechanism remains unclear. Autophagy plays an important role in CKD. However, there were some important related issues that r...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tu, Yue, Gu, Liubao, Chen, Diping, Wu, Wei, Liu, Hong, Hu, Hao, Wan, Yigang, Sun, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5333140/
https://ncbi.nlm.nih.gov/pubmed/28252052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43790
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