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Rhein Inhibits Autophagy in Rat Renal Tubular Cells by Regulation of AMPK/mTOR Signaling

Rhubarb and its bioactive component rhein are frequently used for the treatment of chronic kidney diseases (CKD) in eastern Asia countries. However, the potential therapeutic mechanism remains unclear. Autophagy plays an important role in CKD. However, there were some important related issues that r...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Tu, Yue, Gu, Liubao, Chen, Diping, Wu, Wei, Liu, Hong, Hu, Hao, Wan, Yigang, Sun, Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5333140/
https://ncbi.nlm.nih.gov/pubmed/28252052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43790
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