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Rhein Inhibits Autophagy in Rat Renal Tubular Cells by Regulation of AMPK/mTOR Signaling

Rhubarb and its bioactive component rhein are frequently used for the treatment of chronic kidney diseases (CKD) in eastern Asia countries. However, the potential therapeutic mechanism remains unclear. Autophagy plays an important role in CKD. However, there were some important related issues that r...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Tu, Yue, Gu, Liubao, Chen, Diping, Wu, Wei, Liu, Hong, Hu, Hao, Wan, Yigang, Sun, Wei
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5333140/
https://ncbi.nlm.nih.gov/pubmed/28252052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43790
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