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Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme.

Nitric oxide mediates vascular relaxing effects of endothelial cells, cytotoxic actions of macrophages and neutrophils, and influences of excitatory amino acids on cerebellar cyclic GMP. Its enzymatic formation from arginine by a soluble enzyme associated with stoichiometric production of citrulline...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Bredt, D S, Snyder, S H
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1990
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53329/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1689048/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.2.682
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