Stimulation of β-adrenergic receptors plays a protective role via increased expression of RAF-1 and PDX-1 in hyperglycemic rat pancreatic islet (RIN-m5F) cells

INTRODUCTION: It is a widely held view that a progressive reduction of beta-cell mass occurs in the progression of diabetes. RAF-1 kinase and pancreas duodenal homeobox 1 (PDX-1) are major factors that promote survival of cells and maintain normal insulin functions. In this study we investigated the...

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Bibliografiske detaljer
Udgivet i:Arch Med Sci
Main Authors: Safi, Sher Zaman, Qvist, Rajes, Ong, Gracie, Karimian, Hamed, Imran, Muhammad, Shah, Ikram
Format: Artigo
Sprog:Inglês
Udgivet: Termedia Publishing House 2016
Fag:
Experimental Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5332455/
https://ncbi.nlm.nih.gov/pubmed/28261303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/aoms.2016.64131
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