An Integrated Experimental Design for the Assessment of Multiple Toxicological End Points in Rat Bioassays

BACKGROUND: For nearly five decades long-term studies in rodents have been the accepted benchmark for assessing chronic long-term toxic effects, particularly carcinogenicity, of chemicals. The European Food Safety Authority (EFSA) and the World Health Organization (WHO) have pointed out that the cur...

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Vydáno v:Environ Health Perspect
Hlavní autoři: Manservisi, Fabiana, Marquillas, Clara Babot, Buscaroli, Annalisa, Huff, James, Lauriola, Michelina, Mandrioli, Daniele, Manservigi, Marco, Panzacchi, Simona, Silbergeld, Ellen K., Belpoggi, Fiorella
Médium: Artigo
Jazyk:Inglês
Vydáno: National Institute of Environmental Health Sciences 2016
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Commentary
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5332192/
https://ncbi.nlm.nih.gov/pubmed/27448388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/EHP419
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