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Two oncogenes, v-fos and v-ras, cooperate to convert normal keratinocytes to squamous cell carcinoma.

Previous studies have implicated the rasHa oncogene in the initiation of skin carcinogenesis and the fos oncogene in malignant progression of premalignant skin cell lines. To determine if these two oncogenes are sufficient to convert normal keratinocytes to cancer cells, freshly isolated mouse kerat...

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Autors principals: Greenhalgh, D A, Welty, D J, Player, A, Yuspa, S H
Format: Artigo
Idioma:Inglês
Publicat: 1990
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC53321/
https://ncbi.nlm.nih.gov/pubmed/2153961
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