Repair of critical sized cranial defects with BMP9-transduced calvarial cells delivered in a thermoresponsive scaffold

Large skeletal defects caused by trauma, congenital malformations, and post-oncologic resections of the calvarium present major challenges to the reconstructive surgeon. We previously identified BMP-9 as the most osteogenic BMP in vitro and in vivo. Here we sought to investigate the bone regenerativ...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Dumanian, Zari P., Tollemar, Viktor, Ye, Jixing, Lu, Minpeng, Zhu, Yunxiao, Liao, Junyi, Ameer, Guillermo A., He, Tong-Chuan, Reid, Russell R.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5332017/
https://ncbi.nlm.nih.gov/pubmed/28249039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172327
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