Narciclasine attenuates diet-induced obesity by promoting oxidative metabolism in skeletal muscle

Obesity develops when caloric intake exceeds metabolic needs. Promoting energy expenditure represents an attractive approach in the prevention of this fast-spreading epidemic. Here, we report a novel pharmacological strategy in which a natural compound, narciclasine (ncls), attenuates diet-induced o...

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Veröffentlicht in:PLoS Biol
Hauptverfasser: Julien, Sofi G., Kim, Sun-Yee, Brunmeir, Reinhard, Sinnakannu, Joanna R., Ge, Xiaojia, Li, Hongyu, Ma, Wei, Yaligar, Jadegoud, KN, Bhanu Prakash, Velan, Sendhil S., Röder, Pia V., Zhang, Qiongyi, Sim, Choon Kiat, Wu, Jingyi, Garcia-Miralles, Marta, Pouladi, Mahmoud A., Xie, Wei, McFarlane, Craig, Han, Weiping, Xu, Feng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331945/
https://ncbi.nlm.nih.gov/pubmed/28207742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002597
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