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Increased precursor microRNA-21 following status epilepticus can compete with mature microRNA-21 to alter translation
MicroRNA-21 (miR-21) is consistently up-regulated in various neurological disorders, including epilepsy. Here, we show that the biogenesis of miR-21 is altered following pilocarpine status epilepticus (SE) with an increase in precursor miR-21 (pre-miR-21) in rats. We demonstrate that pre-miR-21 has...
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| Publicado no: | Exp Neurol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5331941/ https://ncbi.nlm.nih.gov/pubmed/27725160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2016.10.003 |
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