Endoplasmic Reticulum Stress Regulates Hepatic Bile Acid Metabolism in Mice

BACKGROUND & AIMS: Cholestasis promotes endoplasmic reticulum (ER) stress in the liver, however, the effect of ER stress on hepatic bile acid metabolism is unknown. We aim to determine the effect of ER stress on hepatic bile acid synthesis and transport in mice. METHODS: ER stress was induced ph...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cell Mol Gastroenterol Hepatol
Auteurs principaux: Henkel, Anne S., LeCuyer, Brian, Olivares, Shantel, Green, Richard M.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2016
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331781/
https://ncbi.nlm.nih.gov/pubmed/28275692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2016.11.006
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