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Characterization of Engineered PreQ1 Riboswitches for Inducible Gene Regulation in Mycobacteria

We report here the behavior of naturally occurring and rationally engineered preQ1 riboswitches and their application to inducible gene regulation in mycobacteria. Because mycobacteria lack preQ1 biosynthetic genes, we hypothesized that preQ1 could be used as an exogenous nonmetabolite ligand to con...

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Detalles Bibliográficos
Publicado en:J Bacteriol
Main Authors: Van Vlack, Erik R., Topp, Shana, Seeliger, Jessica C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331669/
https://ncbi.nlm.nih.gov/pubmed/28069821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00656-16
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