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RNA-protein binding motifs mining with a new hybrid deep learning based cross-domain knowledge integration approach

BACKGROUND: RNAs play key roles in cells through the interactions with proteins known as the RNA-binding proteins (RBP) and their binding motifs enable crucial understanding of the post-transcriptional regulation of RNAs. How the RBPs correctly recognize the target RNAs and why they bind specific po...

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Bibliographic Details
Published in:BMC Bioinformatics
Main Authors: Pan, Xiaoyong, Shen, Hong-Bin
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331642/
https://ncbi.nlm.nih.gov/pubmed/28245811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1561-8
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