Elevated expression of TIGIT on CD3(+)CD4(+) T cells correlates with disease activity in systemic lupus erythematosus

OBJECTIVES: It is well-known that lymphocytes play an important role in systemic lupus erythematosus (SLE). T cell immunoreceptor with Ig and immunoreceptor tyrosine-based inhibitory domains (TIGIT) is one of immunosuppressive costimulatory molecules that mediates an inhibitory effect. However, its...

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Enregistré dans:
Détails bibliographiques
Publié dans:Allergy Asthma Clin Immunol
Auteurs principaux: Luo, Qing, Ye, Jianqing, Zeng, Lulu, Li, Xue, Fang, Le, Ju, Beihua, Huang, Zikun, Li, Junming
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331638/
https://ncbi.nlm.nih.gov/pubmed/28261278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13223-017-0188-7
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