Effects of sarcosine and N, N-dimethylglycine on NMDA receptor-mediated excitatory field potentials

BACKGROUND: Sarcosine, a glycine transporter type 1 inhibitor and an N-methyl-D-aspartate (NMDA) receptor co-agonist at the glycine binding site, potentiates NMDA receptor function. Structurally similar to sarcosine, N,N-dimethylglycine (DMG) is also N-methyl glycine-derivative amino acid and common...

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Vydáno v:J Biomed Sci
Hlavní autoři: Lee, Mei-Yi, Lin, Yi-Ruu, Tu, Yi-Shu, Tseng, Yufeng Jane, Chan, Ming-Huan, Chen, Hwei-Hsien
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331637/
https://ncbi.nlm.nih.gov/pubmed/28245819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-016-0314-8
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