A High-Capacity Adenoviral Hybrid Vector System Utilizing the Hyperactive Sleeping Beauty Transposase SB100X for Enhanced Integration

For efficient delivery of required genetic elements we utilized high-capacity adenoviral vectors in the past allowing high transgene capacities of up to 36 kb. Previously we explored the hyperactive Sleeping Beauty (SB) transposase (HSB5) for somatic integration from the high-capacity adenoviral vec...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Ther Nucleic Acids
Auteurs principaux: Boehme, Philip, Zhang, Wenli, Solanki, Manish, Ehrke-Schulz, Eric, Ehrhardt, Anja
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330939/
https://ncbi.nlm.nih.gov/pubmed/27434682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2016.44
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