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Sildenafil therapy for fetal cardiovascular dysfunction during hypoxic development: studies in the chick embryo

KEY POINTS: Common complications of pregnancy, such as chronic fetal hypoxia, trigger a fetal origin of cardiovascular dysfunction and programme cardiovascular disease in later life. Sildenafil treatment protects placental perfusion and fetal growth, but whether the effects of sildenafil transcend t...

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Bibliographic Details
Published in:J Physiol
Main Authors: Itani, Nozomi, Skeffington, Katie L., Beck, Christian, Giussani, Dino A.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330925/
https://ncbi.nlm.nih.gov/pubmed/27861916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP273393
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