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Investigating the mechanism of ADP-forming acetyl-CoA synthetase from the protozoan parasite Entamoeba histolytica

ADP-forming acetyl-CoA synthetase (ACD) catalyzes the interconversion of acetyl-CoA and acetate. The related succinyl-CoA synthetase follows a three-step mechanism involving a single phosphoenzyme, but a novel four-step mechanism with two phosphoenzyme intermediates was proposed for Pyrococcus ACD....

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Publicat a:FEBS Lett
Autors principals: Jones, Cheryl P., Khan, Kirin, Ingram-Smith, Cheryl
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330840/
https://ncbi.nlm.nih.gov/pubmed/28129670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12573
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