MiR-17-92 cluster in exosomes enhance neuroplasticity and functional recovery after stroke in rats

BACKGROUND AND PURPOSE: Multipotent mesenchymal stromal cell (MSC) harvested exosomes are hypothesized as the major paracrine effectors of MSCs. In vitro, the miR-17-92 cluster promotes oligodendrogenesis, neurogenesis and axonal outgrowth. We therefore investigated whether the miR-17-92 cluster enr...

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Vydáno v:Stroke
Hlavní autoři: Xin, Hongqi, Katakowski, Mark, Wang, Fengjie, Qian, Jian-Yong, Shuang Liu, Xian, Ali, Meser M., Buller, Benjamin, Zhang, Zheng Gang, Chopp, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330787/
https://ncbi.nlm.nih.gov/pubmed/28232590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.116.015204
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