Transcription factor NFAT5 promotes macrophage survival in rheumatoid arthritis

Defective apoptotic death of activated macrophages has been implicated in the pathogenesis of rheumatoid arthritis (RA). However, the molecular signatures defining apoptotic resistance of RA macrophages are not fully understood. Here, global transcriptome profiling of RA macrophages revealed that th...

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Pubblicato in:J Clin Invest
Autori principali: Choi, Susanna, You, Sungyong, Kim, Donghyun, Choi, Soo Youn, Kwon, H. Moo, Kim, Hyun-Sook, Hwang, Daehee, Park, Yune-Jung, Cho, Chul-Soo, Kim, Wan-Uk
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330733/
https://ncbi.nlm.nih.gov/pubmed/28192374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI87880
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